TANYA'S

COMPREHENSIVE GUIDE TO

FELINE CHRONIC KIDNEY DISEASE

 
   

RESEARCH PARTICIPATION OPPORTUNITIES

 

ON THIS PAGE:


Attendance Necessary: Colorado State University (Stem Cell Therapy, Urine Cultures);

Animal Medical Center

(Stem Cell Therapy)


Attendance Not Required: (Maropitant for Nausea and Vomiting Study, Kidney Samples from Deceased Cats (Free Cremation)


 

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WHAT IS CKD?


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Acute Kidney Injury


 

KEY ISSUES


Nausea, Vomiting, Appetite Loss and Excess Stomach Acid


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SYMPTOMS


Alphabetical List of Symptoms and Treatments


Fluid and Urinary  Imbalances (Dehydration, Overhydration and Urinary Issues)


Waste Product Regulation Imbalances (Vomiting, Appetite Loss, Excess Stomach Acid, Gastro-intestinal Problems, Mouth Ulcers Etc.)


Phosphorus and Calcium Imbalances


Miscellaneous Symptoms (Pain, Hiding Etc.)


 

DIAGNOSIS: WHAT DO ALL THE TEST RESULTS MEAN?


Blood Chemistry: Kidney Function, Potassium, Other Tests (ALT, Amylase, (Cholesterol, Etc.)


Calcium, Phosphorus, Parathyroid Hormone (PTH) and Secondary Hyperparathyroidism


Complete Blood Count (CBC): Red and White Blood Cells: Anaemia and Infection


Urinalysis (Urine Tests)


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Renomegaly (Enlarged Kidneys)


Which Tests to Have and Frequency of Testing


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International and US Measuring Systems


 

TREATMENTS


Which Treatments are Essential


Fluid and Urinary Issues (Fluid Retention, Infections, Incontinence, Proteinuria)


Waste Product Regulation (Mouth Ulcers, GI Bleeding, Antioxidants, Adsorbents, Azodyl, Astro's CRF Oil)


Phosphorus, Calcium and Secondary Hyperparathyroidism (Calcitriol)


Miscellaneous Treatments: Stem Cell Transplants, ACE Inhibitors - Fortekor, Steroids, Kidney Transplants)


Antibiotics and Painkillers


Holistic Treatments (Including Slippery Elm Bark)


ESAs (Aranesp, Epogen etc.) for Severe Anaemia


General Health Issues in a CKD Cat: Fleas, Arthritis, Dementia, Vaccinations


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DIET & NUTRITION


Nutritional Requirements of CKD Cats


The B Vitamins (Including Methylcobalamin)


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FLUID THERAPY


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Subcutaneous Fluids - Winning Your Vet's Support


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Home > Research Participation Opportunities

 


Overview


  • It is possible to participate in research studies, both to help your cat and to help other CKD cats who should benefit from the research findings.

  • With some studies, you will need to attend the research facility, normally one of the main US vet schools. However, distance participation is possible with some of the studies.


Studies Where Attendance is Necessary                                                        Back to Page Index


 

Colorado State University:

Animal Medical Center, NYC:

University of Wisconsin-Madison:

Urine Culture Techniques Study - Colorado State University


The Veterinary Teaching Hospital at Colorado State University is seeking volunteers for a study into the diagnosis of pyelonephritis. The study will compare a new urine test to standard tests to see if the new test might more accurately diagnose the infection.

Cats with pyelonephritis or a urinary tract infection are eligible to participate, as are cats with suspected pyelonephritis. but cats who have previously been given antibiotics are not eligible. The laboratory tests required for the study and a kidney ultrasound will be provided free of charge.

If you wish to participate, please call 970-297-5000 and say that you would like to schedule an appointment for Dr. Quimby's urine culture techniques study.

 

Stem Cell Therapy


There are two participation opportunities, as follows:

 

Stem Cell Therapy - Colorado State University


Cats with stable chronic kidney disease can participate in this stem cell study. Cats will receive three IV injections of stem cells over several visits to the veterinarian while their kidney function is monitored.

 

Cats with some other illnesses or heart disease, kidney infection, stones or other renal complications cannot be enrolled in this study.

 

This study involves five visits to the Veterinary Teaching Hospital, so cats that become agitated during veterinary visits are not ideal.

 

All visits, lab work needed for the study, stem cell treatments and a $200 stipend for the owner’s expenses are paid for by CSU’s Frankie’s Fund for Feline Stem Cell Research and the Morris Animal Foundation.

 

If you wish to participate, please call 970-297-5000 and say that you would like to schedule an appointment for Dr. Quimby's stem cell therapy study.

 

Stem Cell Therapy - Animal Medical Center, NYC


Animal Medical Center is offering free stem cell treatment and three years long term management for qualifying cats.

 

The cat needs to be in IRIS Stage 3 (i.e. creatinine level between 2.9 and 5.0) and must have a negative urine culture. The cat must have no history of stones or any other illness, although hypertension or proteinuria are acceptable.

 

The stem cells will be obtained and grown from the cat's own fat, and will be transplanted into the cat's renal artery via the femoral artery. This procedure will be repeated 2.5 weeks later. Follow up care will be available free of charge for three years. Only approved treatments and supplements may be used during this period.

 

Oxidative Stress Study


University of Wisconsin-Madison School of Veterinary Medicine is seeking participants for a trial into oxidative stress. In humans, it is known that the degree of oxidative stress reflects the stage of CKD. The study aims to measure a biomarker of oxidative stress in the kidney called urinary F2-Isoprostanes (F2-IsoP) to see whether the same correlation exists in cats. In due course this may lead to trials of antioxidants.

 

Cats with a urine specific gravity below 1.030 and with no other diseases such as hyperthyroidism, heart disease or diabetes mellitus  are eligible for enrollment. You will receive a free exam by a veterinary internist or internal medicine resident, a number of tests (complete blood count, chemistry panel, urinalysis, urine culture, and total T4), IRIS substaging (blood pressure and urine protein:creatinine) and the Urinary F2-IsoP assay.

 

Contact details are Dr Kelly Monaghan or Dr Will Whitehouse at 1-608-263-7600, or saim@vetmed.wisc.edu.

 

There is more information about the study here.

 


Studies Which Do Not Require Attendance                                                     Back to Page Index


Stem Cell Therapy


ReGena-Vet Laboratories are looking to enrol 12 cats in the San Francisco area into a clinical trial. The cats will be treated by their own vets, who therefore need to be prepared to liaise with ReGena-Vet Laboratories.

 

The trial will require daily injections and bloodtests every two weeks. If you are interested, contact Dr Richard Vulliet on 1-530-902-9006 or at regenavetlabs@gmail.com

 

Maropitant (Cerenia) for Nausea and Vomiting


The Veterinary Teaching Hospital at Colorado State University is seeking volunteers for a study into the use of maropitant for the treatment of nausea and vomiting in cats with CKD.

 

Cats that have been diagnosed with stable chronic kidney disease and who have a “picky” appetite, nausea or vomiting, are potentially eligible for entry into this study. Cats with other illnesses may not be eligible.

 

The cat will be given a complimentary physical exam and chemistry panel at the beginning of the study. The study involves giving cats either maropitant or a placebo daily for two weeks. After two weeks, the cat will receive a second complimentary physical exam and complimentary blood tests (blood chemistry panel). During the study, the owner will be asked to fill out a daily diary of the cat’s behavior and other details.

 

Owners receive complimentary veterinary visits and chemistry tests; a $100 stipend is offered to the participating veterinarian per cat enrolled to cover these costs.

 

If you wish to participate, please contact Dr Jessica Quimby on 970-297-5000 or at jquimby@colostate.edu.

 

Kidney Samples from Deceased Cats (Free Private Cremation)


The Veterinary Teaching Hospital at Colorado State University is researching something called cell senescence. In order to do this, the researchers need to obtain kidney samples from deceased cats. The ashes of the deceased cat would be returned to owners within about a week.

 

The kidney samples would also help with studies into whether nausea and lack of appetite in cats with CKD are caused by a specific condition, and to better understand the stages of kidney disease.

 

If you wish to assist, please contact Dr Jessica Quimby on 970-297-5000 or at jquimby@colostate.edu.

 

 

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This page last updated: 15 September 2013

Links on this page last checked: 20 April 2012